Redirect Loop on Reverse Proxy

I was wondering if anyone has experience hosting Pressbooks behind a reverse proxy. Pressbooks is one of several publishing platforms we use at the press, and keep all of them on different machines behind a reverse proxy. To support this configuration, we have Pressbooks installed using the sub-directory formula for multisite. This set up continues to works fine in our development environment (which isn’t behind a reverse proxy) but after updating to 6.4.0 in production we are having an issue with the home page producing a redirect loop.

I know there has been some recent work on redirects. Before I get too much in the weeds with our infrastructure team, does anyone have any advice?